The sophomore receiver caught 16 passes for a Pac 12-record 345 yards against Arizona. He finished with 469 all-purpose yards thanks to his three kick returns for 123 yards, including a 72-yarder that set up the Trojans' last touchdown in a 39-36 loss.
No Football Bowl Subdivision player had piled up as many receiving yards in a game since Donnie Avery of Houston had 346 against Rice in 2007, according to STATS LLC.
Lee's all-purpose yardage was the most since Reggie Bush, another USC Trojan, piled up 513 against Fresno State in 2005.
Despite his big game against Arizona and two other 190-plus-yard receiving games, Lee is well behind national leader Terrence Williams of Baylor.
Williams averages 171.9 yards receiving. Lee is second at 141.1.
The second-best receiving performance of the week also came in that USC-Arizona game. The Wildcats' Austin Hill had 10 catches for 259 yards.
HAPPY RETURNS: Utah's Reggie Dunn had two 100-yard kickoff returns in a 49-27 win over California and now has three in his career.
He's the 16th player in NCAA history to record two touchdowns on kick returns in a game.
Dunn totaled 222 kick return yards on three returns, setting both an NCAA record and school record for kickoff return average in a game (74.0).
MICHIGAN MALAISE: Michigan has gone two straight games without a touchdown the Wolverines' longest drought since 1962.
Their most recent TD came in the fourth quarter of a 45-0 win over Illinois on Oct. 13. All the Wolverines could muster against Michigan State (12-10 win) and Nebraska (23-9 loss) was a combined seven field goals.
The last time Michigan went without a touchdown for so long was during the 2-7 campaign in 1962, when Michigan State, Purdue and Minnesota shut out the Wolverines in succession.
TACKLE MACHINES: Three of the season's top four tackle performances occurred this past weekend, two of them by teammates.
Nevada's Albert Rosette made a school-record 25 tackles and fellow Wolf Pack linebacker Dray Bell 22 in a 48-31 loss to Air Force. Bell, a senior, was making his first career start.
UAB linebacker Marvin Burdette made a school-record 24 tackles in a 55-45 loss to Tulane. His big outing followed consecutive 17-tackle outings against East Carolina and Houston.
Burdette averages a nation-leading 13 tackles.
FUMBLE PHENOM: Iowa State defensive back Durrell Givens is one of those guys who just has a nose for the football. The senior from Long Beach, Calif., recovered two fumbles and forced another in the Cyclones' 35-21 win over Baylor.
Givens leads the nation with five fumble recoveries in eight games. He has forced three fumbles, tying for 17th.
HIGH-SCORING DUCKS: Oregon's 70-14 win over Colorado padded the Ducks' status as the highest scoring team in the land.
They're averaging 53.4 points a game, just ahead of Louisiana Tech.