OHSU researchers study promising method for male contraception

FILE - Birth control pills

PORTLAND, Ore. – Oregon State University researchers are working to develop a form of male contraceptive.

The work was published in the journal PLOS ONE Thursday. Researchers say they’ve identified a compound called EP055 that binds to sperm proteins in male nonhuman primates and slows the sperm’s mobility.

They say 30 hours after they performed high-dose injections of EP055 on primates, they found that the sperm cells were not able to move around normally. Researchers say they also did not see any physical side effects 18 days after the injection.

The lead investigator, Dr. Michael O’Rand, said there’s still more work required before EP055 becomes available for human use. The team has begun to test a pill on primates and will eventually conduct a mating trial to test its true effectiveness against pregnancy.

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